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Insight into molecular dynamics simulation of BRAF(V600E) and potent novel inhibitors for malignant melanoma
BRAF inhibitors have changed the standard therapeutic protocol for advanced or metastatic melanoma which harbored notorious BRAF(V600E) single mutation. However, drug resistance to BRAF inhibitors happens just like other cancer treatment. In this study, we constructed the ideal BRAF(V600E)-modeled s...
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| Publicado no: | Int J Nanomedicine |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4412490/ https://ncbi.nlm.nih.gov/pubmed/25960652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S80150 |
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