Activation of autophagy protects against cholestasis-induced hepatic injury

BACKGROUND: Cholestasis is characterized by an abnormal accumulation of bile acids and causes hepatocellular injury. Recent studies show that autophagy is involved in the pathophysiology of many liver diseases. The potential role of autophagy in preventing cholestatic hepatotoxicity, however, has ra...

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Gao, Lu, Lv, Gang, Guo, Xianling, Jing, Yingying, Han, Zhipeng, Zhang, Shanshan, Sun, Kai, Li, Rong, Yang, Yang, Wei, Lixin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4412295/
https://ncbi.nlm.nih.gov/pubmed/25922659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-4-47
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