Simvastatin protects against cholestasis-induced liver injury

BACKGROUND: Bile duct obstruction is associated with hepatic accumulation of leukocytes and liver injury. The aim of this study was to evaluate the effect of simvastatin on cholestasis-induced liver inflammation and tissue damage. EXPERIMENTAL APPROACH: C57BL/6 mice were treated with simvastatin (0....

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Bibliographic Details
Main Authors: Dold, S, Laschke, MW, Lavasani, S, Menger, MD, Jeppsson, B, Thorlacius, H
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697675/
https://ncbi.nlm.nih.gov/pubmed/19154429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2008.00043.x
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