The role of AKT1 and autophagy in the protective effect of hydrogen sulphide against hepatic ischemia/reperfusion injury in mice

Hydrogen sulphide (H(2)S) exerts a protective effect in hepatic ischemia-reperfusion (I/R) injury. However, the exact mechanism of H(2)S action remains largely unknown. This study was designed to investigate the role of the PtdIns3K-AKT1 pathways and autophagy in the protective effect of H(2)S again...

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Autors principals: Wang, Dawei, Ma, Yong, Li, Zhengtian, Kang, Kai, Sun, Xueying, Pan, Shangha, Wang, Jizhou, Pan, Huayang, Liu, Lianxin, Liang, Desen, Jiang, Hongchi
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Basic Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427260/
https://ncbi.nlm.nih.gov/pubmed/22694815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19927
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