Positive and negative transcriptional control by the TAL1 helix-loop-helix protein.

Tumor-specific activation of the TAL1 gene is the most common genetic defect associated with T-cell acute lymphoblastic leukemia. The TAL1 gene products possess a basic helix-loop-helix (bHLH) motif, a protein-dimerization and DNA-binding domain found in several transcription factors. TAL1 polypepti...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hsu, H L, Wadman, I, Tsan, J T, Baer, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44114/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.5947
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