The Structure of the PanD/PanZ Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A

Coenzyme A (CoA) is an ubiquitous and essential cofactor, synthesized from the precursor pantothenate. Vitamin biosynthetic pathways are normally tightly regulated, including the pathway from pantothenate to CoA. However, no regulation of pantothenate biosynthesis has been identified. We have recent...

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Bibliografske podrobnosti
izdano v:Chem Biol
Main Authors: Monteiro, Diana C.F., Patel, Vijay, Bartlett, Christopher P., Nozaki, Shingo, Grant, Thomas D., Gowdy, James A., Thompson, Gary S., Kalverda, Arnout P., Snell, Edward H., Niki, Hironori, Pearson, Arwen R., Webb, Michael E.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410942/
https://ncbi.nlm.nih.gov/pubmed/25910242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.03.017
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