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The use of hybrid Virus-like Particles to enhance the immunogenicity of a broadly protective HPV vaccine

Virus-like particles (VLPs) can serve as a highly immunogenic vaccine platform for the multivalent display of epitopes from pathogens. We have used bacteriophage VLPs to develop vaccines that target a highly conserved epitope from the Human Papillomavirus (HPV) minor capsid protein, L2. VLPs display...

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Publicat a:Biotechnol Bioeng
Autors principals: Tyler, Mitchell, Tumban, Ebenezer, Peabody, David S., Chackerian, Bryce
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410690/
https://ncbi.nlm.nih.gov/pubmed/24917327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25311
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