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A Universal Virus-Like Particle-based Vaccine for Human Papillomavirus: Longevity of Protection and Role of Endogenous and Exogenous Adjuvants

Antibodies targeting epitopes within the amino terminus of the minor capsid protein L2 of human papillomavirus (HPV) are broadly neutralizing against diverse HPV isolates. We have constructed bacteriophage virus-like particle (VLP)-based vaccines that display short L2 peptides and elicit high-titer...

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Библиографические подробности
Главные авторы: Tumban, Ebenezer, Peabody, Julianne, Peabody, David S., Chackerian, Bryce
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785330/
https://ncbi.nlm.nih.gov/pubmed/23933337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.07.052
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