A Universal Virus-Like Particle-based Vaccine for Human Papillomavirus: Longevity of Protection and Role of Endogenous and Exogenous Adjuvants

Antibodies targeting epitopes within the amino terminus of the minor capsid protein L2 of human papillomavirus (HPV) are broadly neutralizing against diverse HPV isolates. We have constructed bacteriophage virus-like particle (VLP)-based vaccines that display short L2 peptides and elicit high-titer...

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Bibliographic Details
Main Authors: Tumban, Ebenezer, Peabody, Julianne, Peabody, David S., Chackerian, Bryce
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785330/
https://ncbi.nlm.nih.gov/pubmed/23933337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.07.052
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