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The use of hybrid Virus-like Particles to enhance the immunogenicity of a broadly protective HPV vaccine

Virus-like particles (VLPs) can serve as a highly immunogenic vaccine platform for the multivalent display of epitopes from pathogens. We have used bacteriophage VLPs to develop vaccines that target a highly conserved epitope from the Human Papillomavirus (HPV) minor capsid protein, L2. VLPs display...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Tyler, Mitchell, Tumban, Ebenezer, Peabody, David S., Chackerian, Bryce
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410690/
https://ncbi.nlm.nih.gov/pubmed/24917327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25311
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