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SIRT1 Mediates a Primed Response to Immune Challenge after Traumatic Lung Injury
BACKGROUND: Pulmonary contusion (PC) is a common, potentially lethal injury that results in priming for exaggerated inflammatory responses to subsequent immune challenge like infection (2(nd) hit). The molecular mechanism of priming and the 2(nd) hit phenomenon after PC remain obscure. Using a mouse...
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| Publicado no: | J Trauma Acute Care Surg |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4410426/ https://ncbi.nlm.nih.gov/pubmed/25909427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000000598 |
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