The long-acting β(2)-adrenoceptor agonist, indacaterol, enhances glucocorticoid receptor-mediated transcription in human airway epithelial cells in a gene- and agonist-dependent manner

BACKGROUND AND PURPOSE: Inhaled glucocorticoid (ICS)/long-acting β(2)-adrenoceptor agonist (LABA) combination therapy is a recommended treatment option for patients with moderate/severe asthma in whom adequate control cannot be achieved by an ICS alone. Previously, we discovered that LABAs can augme...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Main Authors: Joshi, T, Johnson, M, Newton, R, Giembycz, M A
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2015
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409912/
https://ncbi.nlm.nih.gov/pubmed/25598440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13087
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