An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles with implications for asthma therapeutics

BACKGROUND AND PURPOSE: International asthma guidelines recommend that inhaled glucocorticoids be used as a monotherapy in all patients with mild to moderate disease because of their ability to suppress airways inflammation. Current evidence suggests that the therapeutic benefit of glucocorticoids i...

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Publicado en:Br J Pharmacol
Autores principales: Joshi, T, Johnson, M, Newton, R, Giembycz, M
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337707/
https://ncbi.nlm.nih.gov/pubmed/25393397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13014
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