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An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles with implications for asthma therapeutics

BACKGROUND AND PURPOSE: International asthma guidelines recommend that inhaled glucocorticoids be used as a monotherapy in all patients with mild to moderate disease because of their ability to suppress airways inflammation. Current evidence suggests that the therapeutic benefit of glucocorticoids i...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Br J Pharmacol
मुख्य लेखकों: Joshi, T, Johnson, M, Newton, R, Giembycz, M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BlackWell Publishing Ltd 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337707/
https://ncbi.nlm.nih.gov/pubmed/25393397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13014
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