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GPCR dimerization in brainstem nuclei contributes to the development of hypertension
BACKGROUND AND PURPOSE: μ-Opioid receptors, pro-opiomelanocortin and pro-enkephalin are highly expressed in the nucleus tractus solitarii (NTS) and μ receptor agonists given to the NTS dose-dependently increased BP. However, the molecular mechanisms of this process remain unclear. In vitro, μ recept...
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| Publicado en: | Br J Pharmacol |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BlackWell Publishing Ltd
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409903/ https://ncbi.nlm.nih.gov/pubmed/25573074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13074 |
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