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Resveratrol Inhibition of Rac1-Derived Reactive Oxygen Species by AMPK Decreases Blood Pressure in a Fructose-Induced Rat Model of Hypertension

Recent studies have reported that the activation of AMP-activated protein kinase (AMPK) suppressed oxidative stress. The aim of this study was to examine whether the activation of AMPK in the brain decreased Rac1-induced ROS generation, thereby reducing blood pressure (BP) in rats with fructose-indu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cheng, Pei-Wen, Lee, Hui-Chieh, Lu, Pei-Jung, Chen, Hsin-Hung, Lai, Chi-Cheng, Sun, Gwo-Ching, Yeh, Tung-Chen, Hsiao, Michael, Lin, Yu-Te, Liu, Chun-Peng, Tseng, Ching-Jiunn
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853785/
https://ncbi.nlm.nih.gov/pubmed/27138844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25342
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