Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells

Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T cell leukemia (ATL), which is an aggressive form of T-cell malignancy. HTLV-1 oncoproteins, Tax and HBZ, play crucial roles in the immortalization of T-cells and/or leukemogenesis by dysregulating the cellular functions...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Takachi, Takayuki, Takahashi, Masahiko, Takahashi-Yoshita, Manami, Higuchi, Masaya, Obata, Miki, Mishima, Yukio, Okuda, Shujiro, Tanaka, Yuetsu, Matsuoka, Masao, Saitoh, Akihiko, Green, Patrick L, Fujii, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409891/
https://ncbi.nlm.nih.gov/pubmed/25613934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12618
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