PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein is essential for the interleukin 2 independent growth induction of a T-cell line

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia (ATL), whereas HTLV type 2 (HTLV-2), is not associated with ATL or any other leukemia. HTLV-1 encodes the transforming gene tax1, whose expression in an interleukin (IL)-2-dependent T-cell line (C...

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Detalhes bibliográficos
Main Authors: Tsubata, Chikako, Higuchi, Masaya, Takahashi, Masahiko, Oie, Masayasu, Tanaka, Yuetsu, Gejyo, Fumitake, Fujii, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199618/
https://ncbi.nlm.nih.gov/pubmed/16042787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-46
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