Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is a causative agent of adult T-cell leukemia (ATL), whereas its relative HTLV-2 is not associated with any malignancies including ATL. HTLV-1 Tax1 transformed a T-cell line from interleukin (IL)-2-dependent growth to IL-2-independent growth, w...

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Hauptverfasser: Shoji, Toshiyuki, Higuchi, Masaya, Kondo, Rie, Takahashi, Masahiko, Oie, Masayasu, Tanaka, Yuetsu, Aoyagi, Yutaka, Fujii, Masahiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754985/
https://ncbi.nlm.nih.gov/pubmed/19761585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-83
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