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Potential antitumor therapeutic application of Grimontia hollisae thermostable direct hemolysin mutants
We report on the preparation of a new type of immunotoxin by conjugation of an epidermal growth factor receptor (EGFR)-binding peptide and an R46E mutation of thermostable direct hemolysin from Grimontia hollisae, (Gh-TDH(R)(46E)/EB). The hybrid immunotoxin was purified to homogeneity and showed a s...
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| Pubblicato in: | Cancer Sci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409889/ https://ncbi.nlm.nih.gov/pubmed/25640743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12623 |
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