Site-Directed Mutations of Thermostable Direct Hemolysin from Grimontia hollisae Alter Its Arrhenius Effect and Biophysical Properties

Recombinant thermostable direct hemolysin from Grimontia hollisae (Gh-rTDH) exhibits paradoxical Arrhenius effect, where the hemolytic activity is inactivated by heating at 60 (o)C but is reactivated by additional heating above 80 (o)C. This study investigated individual or collective mutational eff...

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Detalhes bibliográficos
Main Authors: Wang, Yu-Kuo, Huang, Sheng-Cih, Wu, Yi-Fang, Chen, Yu-Ching, Lin, Yen-Ling, Nayak, Manoswini, Lin, Yan Ren, Chen, Wen-Hung, Chiu, Yi-Rong, Li, Thomas Tien-Hsiung, Yeh, Bo-Sou, Wu, Tung-Kung
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076507/
https://ncbi.nlm.nih.gov/pubmed/21494434
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