Structural basis for protein-RNA recognition in telomerase

Telomerase is a large ribonucleoprotein complex minimally composed of a catalytic telomerase reverse transcriptase (TERT) and an RNA component (TR) that provides the template for telomeric DNA synthesis. However, it remains unclear how TERT and TR assemble into a functional telomerase. Here we repor...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Huang, Jing, Brown, Andrew F, Wu, Jian, Xue, Jing, Bley, Christopher J, Rand, Dustin P, Wu, Lijie, Zhang, Rongguang, Chen, Julian J-L, Lei, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409868/
https://ncbi.nlm.nih.gov/pubmed/24793650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2819
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