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Asymmetric Unwrapping of Nucleosomes under Tension Directed by DNA Local Flexibility
Dynamics of the nucleosome and exposure of nucleosomal DNA play key roles in many nuclear processes but local dynamics of the nucleosome and its modulation by DNA sequence are poorly understood. Using single-molecule assays we observed that the nucleosome can unwrap asymmetrically and directionally...
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| Publicado no: | Cell |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409768/ https://ncbi.nlm.nih.gov/pubmed/25768909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.001 |
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