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Asymmetric unwrapping of nucleosomal DNA propagates asymmetric opening and dissociation of the histone core

The nucleosome core particle (NCP) is the basic structural unit for genome packaging in eukaryotic cells and consists of DNA wound around a core of eight histone proteins. DNA access is modulated through dynamic processes of NCP disassembly. Partly disassembled structures, such as the hexasome (cont...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Yujie, Tokuda, Joshua M., Topping, Traci, Meisburger, Steve P., Pabit, Suzette A., Gloss, Lisa M., Pollack, Lois
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240728/
https://ncbi.nlm.nih.gov/pubmed/28028239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611118114
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