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Asymmetric unwrapping of nucleosomal DNA propagates asymmetric opening and dissociation of the histone core

The nucleosome core particle (NCP) is the basic structural unit for genome packaging in eukaryotic cells and consists of DNA wound around a core of eight histone proteins. DNA access is modulated through dynamic processes of NCP disassembly. Partly disassembled structures, such as the hexasome (cont...

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Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Chen, Yujie, Tokuda, Joshua M., Topping, Traci, Meisburger, Steve P., Pabit, Suzette A., Gloss, Lisa M., Pollack, Lois
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240728/
https://ncbi.nlm.nih.gov/pubmed/28028239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611118114
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