C9orf72 promoter hypermethylation is neuroprotective: Neuroimaging and neuropathologic evidence

OBJECTIVE: To use in vivo neuroimaging and postmortem neuropathologic analysis in C9orf72 repeat expansion patients to investigate the hypothesis that C9orf72 promoter hypermethylation is neuroprotective and regionally selective. METHODS: Twenty patients with a C9orf72 repeat expansion participating...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Neurology
Autori principali: McMillan, Corey T., Russ, Jenny, Wood, Elisabeth M., Irwin, David J., Grossman, Murray, McCluskey, Leo, Elman, Lauren, Van Deerlin, Vivanna, Lee, Edward B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2015
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409587/
https://ncbi.nlm.nih.gov/pubmed/25795648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001495
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi