Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response

Mitochondrial DNA (mtDNA) is normally present at thousands of copies per cell and is packaged into several hundred higher-order structures termed nucleoids(1). The abundant mtDNA-binding protein, transcription factor A mitochondrial (TFAM), regulates nucleoid architecture, abundance, and segregation...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: West, A. Phillip, Khoury-Hanold, William, Staron, Matthew, Tal, Michal C., Pineda, Cristiana M., Lang, Sabine M., Bestwick, Megan, Duguay, Brett A., Raimundo, Nuno, MacDuff, Donna A., Kaech, Susan M., Smiley, James R., Means, Robert E., Iwasaki, Akiko, Shadel, Gerald S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409480/
https://ncbi.nlm.nih.gov/pubmed/25642965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14156
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