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Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response
Mitochondrial DNA (mtDNA) is normally present at thousands of copies per cell and is packaged into several hundred higher-order structures termed nucleoids(1). The abundant mtDNA-binding protein, transcription factor A mitochondrial (TFAM), regulates nucleoid architecture, abundance, and segregation...
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| Pubblicato in: | Nature |
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| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409480/ https://ncbi.nlm.nih.gov/pubmed/25642965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14156 |
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