Plasma TNF-α and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna—A Randomized, Cross-Over Clinical Study

PURPOSE: Chemotherapy-induced cognitive impairment (CICI) is a common sequelae of cancer therapy. Recent preclinical observations have suggested that CICI can be mediated by chemotherapy-induced plasma protein oxidation, which triggers TNF-α mediated CNS damage. This study evaluated sodium-2-mercapt...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hayslip, John, Dressler, Emily V., Weiss, Heidi, Taylor, Tammy J., Chambers, Mara, Noel, Teresa, Miriyala, Sumitra, Keeney, Jeriel T. R., Ren, Xiaojia, Sultana, Rukhsana, Vore, Mary, Butterfield, D. Allan, St Clair, Daret, Moscow, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409356/
https://ncbi.nlm.nih.gov/pubmed/25909710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124988
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