Plasma TNF-α and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna—A Randomized, Cross-Over Clinical Study

PURPOSE: Chemotherapy-induced cognitive impairment (CICI) is a common sequelae of cancer therapy. Recent preclinical observations have suggested that CICI can be mediated by chemotherapy-induced plasma protein oxidation, which triggers TNF-α mediated CNS damage. This study evaluated sodium-2-mercapt...

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Vydáno v:PLoS One
Hlavní autoři: Hayslip, John, Dressler, Emily V., Weiss, Heidi, Taylor, Tammy J., Chambers, Mara, Noel, Teresa, Miriyala, Sumitra, Keeney, Jeriel T. R., Ren, Xiaojia, Sultana, Rukhsana, Vore, Mary, Butterfield, D. Allan, St Clair, Daret, Moscow, Jeffrey A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409356/
https://ncbi.nlm.nih.gov/pubmed/25909710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124988
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