IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans

Lipoprotein (a) [Lp(a)] is a highly atherogenic lipid particle. Although earlier reports suggested that Lp(a) levels are mostly determined by genetic factors, several recent studies have revealed that Lp(a) induction is also caused by chronic inflammation. Therefore, we aimed to examine whether cyto...

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Zapisane w:
Opis bibliograficzny
Wydane w:J Lipid Res
Główni autorzy: Müller, Nike, Schulte, Dominik M., Türk, Kathrin, Freitag-Wolf, Sandra, Hampe, Jochen, Zeuner, Rainald, Schröder, Johann O., Gouni-Berthold, Ioanna, Berthold, Heiner K., Krone, Wilhelm, Rose-John, Stefan, Schreiber, Stefan, Laudes, Matthias
Format: Artigo
Język:Inglês
Wydane: The American Society for Biochemistry and Molecular Biology 2015
Hasła przedmiotowe:
Patient-Oriented and Epidemiological Research
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409280/
https://ncbi.nlm.nih.gov/pubmed/25713100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P052209
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