IL-6 blockade by monoclonal antibodies inhibits apolipoprotein (a) expression and lipoprotein (a) synthesis in humans

Lipoprotein (a) [Lp(a)] is a highly atherogenic lipid particle. Although earlier reports suggested that Lp(a) levels are mostly determined by genetic factors, several recent studies have revealed that Lp(a) induction is also caused by chronic inflammation. Therefore, we aimed to examine whether cyto...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Lipid Res
Main Authors: Müller, Nike, Schulte, Dominik M., Türk, Kathrin, Freitag-Wolf, Sandra, Hampe, Jochen, Zeuner, Rainald, Schröder, Johann O., Gouni-Berthold, Ioanna, Berthold, Heiner K., Krone, Wilhelm, Rose-John, Stefan, Schreiber, Stefan, Laudes, Matthias
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Biochemistry and Molecular Biology 2015
נושאים:
Patient-Oriented and Epidemiological Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409280/
https://ncbi.nlm.nih.gov/pubmed/25713100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P052209
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