Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

Atherosclerosis stems from imbalances in lipid metabolism and leads to maladaptive inflammatory responses. The AMP-activated protein kinase (Ampk) is a highly conserved serine/threonine kinase that regulates many aspects of lipid and energy metabolism, although its specific role in controlling macro...

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Détails bibliographiques
Publié dans:J Lipid Res
Auteurs principaux: Fullerton, Morgan D., Ford, Rebecca J., McGregor, Chelsea P., LeBlond, Nicholas D., Snider, Shayne A., Stypa, Stephanie A., Day, Emily A., Lhoták, Šárka, Schertzer, Jonathan D., Austin, Richard C., Kemp, Bruce E., Steinberg, Gregory R.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2015
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409279/
https://ncbi.nlm.nih.gov/pubmed/25773887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M058875
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