Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes

Doxorubicin (DOX) is a chemotherapeutic agent effective in the treatment of many cancers. However, cardiac dysfunction caused by DOX limits its clinical use. DOX is believed to be harmful to cardiomyocytes by interfering with the mitochondrial phospholipid cardiolipin and causing inefficient electro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Cheung, Kyle G., Cole, Laura K., Xiang, Bo, Chen, Keyun, Ma, Xiuli, Myal, Yvonne, Hatch, Grant M., Tong, Qiang, Dolinsky, Vernon W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Metabolism
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409259/
https://ncbi.nlm.nih.gov/pubmed/25759382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.607960
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