G Protein-coupled Receptor Kinases of the GRK4 Protein Subfamily Phosphorylate Inactive G Protein-coupled Receptors (GPCRs)

G protein-coupled receptor (GPCR) kinases (GRKs) play a key role in homologous desensitization of GPCRs. It is widely assumed that most GRKs selectively phosphorylate only active GPCRs. Here, we show that although this seems to be the case for the GRK2/3 subfamily, GRK5/6 effectively phosphorylate i...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Li, Lingyong, Homan, Kristoff T., Vishnivetskiy, Sergey A., Manglik, Aashish, Tesmer, John J. G., Gurevich, Vsevolod V., Gurevich, Eugenia V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
Onderwerpen:
Signal Transduction
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409243/
https://ncbi.nlm.nih.gov/pubmed/25770216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.644773
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items