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Clostridium perfringens Alpha-Toxin Induces Gm1a Clustering and Trka Phosphorylation in the Host Cell Membrane
Clostridium perfringens alpha-toxin elicits various immune responses such as the release of cytokines, chemokines, and superoxide via the GM1a/TrkA complex. Alpha-toxin possesses phospholipase C (PLC) hydrolytic activity that contributes to signal transduction in the pathogenesis of gas gangrene. Li...
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出版年: | PLoS One |
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主要な著者: | , , , , , , , , , , , |
フォーマット: | Artigo |
言語: | Inglês |
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Public Library of Science
2015
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409118/ https://ncbi.nlm.nih.gov/pubmed/25910247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120497 |
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