Clostridium perfringens Alpha-Toxin Induces Gm1a Clustering and Trka Phosphorylation in the Host Cell Membrane

Clostridium perfringens alpha-toxin elicits various immune responses such as the release of cytokines, chemokines, and superoxide via the GM1a/TrkA complex. Alpha-toxin possesses phospholipase C (PLC) hydrolytic activity that contributes to signal transduction in the pathogenesis of gas gangrene. Li...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Takagishi, Teruhisa, Oda, Masataka, Kabura, Michiko, Kurosawa, Mie, Tominaga, Kaori, Urano, Shiori, Ueda, Yoshibumi, Kobayashi, Keiko, Kobayashi, Toshihide, Sakurai, Jun, Terao, Yutaka, Nagahama, Masahiro
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409118/
https://ncbi.nlm.nih.gov/pubmed/25910247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120497
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