Cortical GABAergic excitation contributes to epileptic activities around human glioma

RATIONALE: Diffuse brain gliomas induce seizures in a majority of patients. As in most epileptic disorders, excitatory glutamatergic mechanisms are involved in the generation of epileptic activities in the neocortex surrounding gliomas. However, chloride homeostasis is known to be perturbed in glial...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Transl Med
Prif Awduron: Pallud, Johan, Le Van Quyen, Michel, Bielle, Franck, Pellegrino, Christophe, Varlet, Pascale, Cresto, Noemie, Baulac, Michel, Duyckaerts, Charles, Kourdougli, Nazim, Chazal, Geneviève, Devaux, Bertrand, Rivera, Claudio, Miles, Richard, Capelle, Laurent, Huberfeld, Gilles
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409113/
https://ncbi.nlm.nih.gov/pubmed/25009229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008065
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