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Cortical GABAergic excitation contributes to epileptic activities around human glioma

RATIONALE: Diffuse brain gliomas induce seizures in a majority of patients. As in most epileptic disorders, excitatory glutamatergic mechanisms are involved in the generation of epileptic activities in the neocortex surrounding gliomas. However, chloride homeostasis is known to be perturbed in glial...

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Bibliografski detalji
Izdano u:Sci Transl Med
Glavni autori: Pallud, Johan, Le Van Quyen, Michel, Bielle, Franck, Pellegrino, Christophe, Varlet, Pascale, Cresto, Noemie, Baulac, Michel, Duyckaerts, Charles, Kourdougli, Nazim, Chazal, Geneviève, Devaux, Bertrand, Rivera, Claudio, Miles, Richard, Capelle, Laurent, Huberfeld, Gilles
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409113/
https://ncbi.nlm.nih.gov/pubmed/25009229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008065
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