Cortical GABAergic excitation contributes to epileptic activities around human glioma

RATIONALE: Diffuse brain gliomas induce seizures in a majority of patients. As in most epileptic disorders, excitatory glutamatergic mechanisms are involved in the generation of epileptic activities in the neocortex surrounding gliomas. However, chloride homeostasis is known to be perturbed in glial...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Pallud, Johan, Le Van Quyen, Michel, Bielle, Franck, Pellegrino, Christophe, Varlet, Pascale, Cresto, Noemie, Baulac, Michel, Duyckaerts, Charles, Kourdougli, Nazim, Chazal, Geneviève, Devaux, Bertrand, Rivera, Claudio, Miles, Richard, Capelle, Laurent, Huberfeld, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409113/
https://ncbi.nlm.nih.gov/pubmed/25009229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008065
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