Purified IgG from Patients with Obstetric but not IgG from Non-obstetric Antiphospholipid Syndrome Inhibit Trophoblast Invasion

PROBLEM: Some patients with antiphospholipid syndrome (APS) suffer pregnancy morbidity (PM) but not vascular thrombosis (VT), whilst others suffer VT only. Therefore, we compared the effects of IgG from VT+/PM− and VT−/PM+ subjects on human first-trimester trophoblast (HTR8) cells. METHOD OF STUDY:...

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Vydáno v:Am J Reprod Immunol
Hlavní autoři: Poulton, Katie, Ripoll, Vera M, Pericleous, Charis, Meroni, Pier Luigi, Gerosa, Maria, Ioannou, Yiannis, Rahman, Anisur, Giles, Ian P
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Immunological Factors in Pregnancy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409084/
https://ncbi.nlm.nih.gov/pubmed/25469631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aji.12341
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