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Cell-specific nuclear import of plasmid DNA

One factor limiting the success of non-viral gene therapy vectors is the relative inability to target genes specifically to a desired cell type. To address this limitation, we have begun to develop cell-specific vectors whose specificity is at the level of the nuclear import of the plasmid DNA. We h...

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Detalles Bibliográficos
Publicado en:Gene Ther
Main Authors: Vacik, J, Dean, BS, Zimmer, WE, Dean, DA
Formato: Artigo
Idioma:Inglês
Publicado: 1999
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408932/
https://ncbi.nlm.nih.gov/pubmed/10455402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3300924
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