Identification of Protein Cofactors Necessary for Sequence-specific Plasmid DNA Nuclear Import

Although transfections are routinely used in the laboratory, the mechanism(s) by which exogenous DNA is transported into the nucleus is poorly understood. By improving our understanding of how vectors circumvent the numerous cellular barriers to gene transfer, more efficient gene delivery methods ca...

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Bibliographic Details
Main Authors: Miller, Aaron M, Munkonge, Felix M, Alton, Eric WFW, Dean, David A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835029/
https://ncbi.nlm.nih.gov/pubmed/19532138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.127
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