Generic GPCR Residue Numbers - Aligning Topology Maps Minding The Gaps

Generic residue numbers facilitate comparisons of e.g. mutational effects, ligand interactions, and structural motifs. The class A GPCR residue numbering by Ballesteros and Weinstein has more than 1100 citations, and the recent crystal structures for class B, C and F now call for community consensus...

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Publicat a:Trends Pharmacol Sci
Autors principals: Isberg, Vignir, de Graaf, Chris, Bortolato, Andrea, Cherezov, Vadim, Katritch, Vsevolod, Marshall, Fiona H., Mordalski, Stefan, Pin, Jean-Philippe, Stevens, Raymond C., Vriend, Gerrit, Gloriam, David E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408928/
https://ncbi.nlm.nih.gov/pubmed/25541108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2014.11.001
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