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Integrating structural and mutagenesis data to elucidate GPCR ligand binding

G protein-coupled receptors (GPCRs) represent the largest family of human membrane proteins, as well as drug targets. A recent boom in GPCR structural biology has provided detailed images of receptor ligand binding sites and interactions on the molecular level. An ever-increasing number of ligands i...

詳細記述

保存先:
書誌詳細
出版年:Curr Opin Pharmacol
主要な著者: Munk, Christian, Harpsøe, Kasper, Hauser, Alexander, Isberg, Vignir, Gloriam, David E.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910865/
https://ncbi.nlm.nih.gov/pubmed/27475047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.07.003
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