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Integrating structural and mutagenesis data to elucidate GPCR ligand binding
G protein-coupled receptors (GPCRs) represent the largest family of human membrane proteins, as well as drug targets. A recent boom in GPCR structural biology has provided detailed images of receptor ligand binding sites and interactions on the molecular level. An ever-increasing number of ligands i...
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| Publicado en: | Curr Opin Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6910865/ https://ncbi.nlm.nih.gov/pubmed/27475047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.07.003 |
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