High glucose induces mitochondrial dysfunction independently of protein O-GlcNAcylation

Diabetes is characterized by hyperglycaemia and perturbations in intermediary metabolism. In particular, diabetes can augment flux through accessory pathways of glucose metabolism, such as the hexosamine biosynthetic pathway (HBP), which produces the sugar donor for the β-O-linked-N-acetylglucosamin...

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Bibliografski detalji
Izdano u:Biochem J
Glavni autori: Dassanayaka, Sujith, Readnower, Ryan D., Salabei, Joshua K., Long, Bethany W., Aird, Allison L., Zheng, Yu-Ting, Muthusamy, Senthilkumar, Facundo, Heberty T., Hill, Bradford G., Jones, Steven P.
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408906/
https://ncbi.nlm.nih.gov/pubmed/25627821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141018
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