High glucose induces mitochondrial dysfunction independently of protein O-GlcNAcylation

Diabetes is characterized by hyperglycaemia and perturbations in intermediary metabolism. In particular, diabetes can augment flux through accessory pathways of glucose metabolism, such as the hexosamine biosynthetic pathway (HBP), which produces the sugar donor for the β-O-linked-N-acetylglucosamin...

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Detaylı Bibliyografya
Yayımlandı:Biochem J
Asıl Yazarlar: Dassanayaka, Sujith, Readnower, Ryan D., Salabei, Joshua K., Long, Bethany W., Aird, Allison L., Zheng, Yu-Ting, Muthusamy, Senthilkumar, Facundo, Heberty T., Hill, Bradford G., Jones, Steven P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408906/
https://ncbi.nlm.nih.gov/pubmed/25627821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141018
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