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High glucose induces mitochondrial dysfunction independently of protein O-GlcNAcylation
Diabetes is characterized by hyperglycaemia and perturbations in intermediary metabolism. In particular, diabetes can augment flux through accessory pathways of glucose metabolism, such as the hexosamine biosynthetic pathway (HBP), which produces the sugar donor for the β-O-linked-N-acetylglucosamin...
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| Publicado no: | Biochem J |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4408906/ https://ncbi.nlm.nih.gov/pubmed/25627821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141018 |
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