Less Is More: An Adaptive Branch-Site Random Effects Model for Efficient Detection of Episodic Diversifying Selection

Over the past two decades, comparative sequence analysis using codon-substitution models has been honed into a powerful and popular approach for detecting signatures of natural selection from molecular data. A substantial body of work has focused on developing a class of “branch-site” models which p...

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Bibliographic Details
Published in:Mol Biol Evol
Main Authors: Smith, Martin D., Wertheim, Joel O., Weaver, Steven, Murrell, Ben, Scheffler, Konrad, Kosakovsky Pond, Sergei L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Methods
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408413/
https://ncbi.nlm.nih.gov/pubmed/25697341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msv022
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