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Multiple conformations of a single SNAREpin between two nanodisc membranes reveal diverse pre-fusion states

SNAREpins must be formed between two membranes to allow vesicle fusion, a required process for neurotransmitter release. Although its post-fusion structure has been well characterized pre-fusion conformations have been elusive. We used single molecule FRET and EPR to investigate the SNAREpin assembl...

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Veröffentlicht in:Biochem J
Hauptverfasser: Shin, Jaeil, Lou, Xiaochu, Kweon, Dae-Hyuk, Shin, Yeon-Kyun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407826/
https://ncbi.nlm.nih.gov/pubmed/24456382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131668
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