Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate.
The effects of 3'-azido-3'-deoxythymidine (AZT) and three of its intracellular metabolites, azido- thymidine mono-, di-, and triphosphates, on the human immunodeficiency virus type 1 integrase have been determined. AZT mono-, di-, and triphosphate have an IC50 for integration between 110 and 150 mic...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8016063/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.13.5771 |
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