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Synaptic-Type α1β2γ2L GABA(A) Receptors Produce Large Persistent Currents in the Presence of Ambient GABA and Anesthetic Drugs

Synaptic GABA(A) receptors respond to synaptically released GABA and are considered to be unaffected by the low levels of ambient transmitter in the brain. We show that synaptic-type α1β2γ2L GABA(A) receptors expressed in HEK293 cells respond with large steady-state currents to combinations of a low...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Li, Ping, Akk, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4407730/
https://ncbi.nlm.nih.gov/pubmed/25667223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.096453
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