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Protein Kinase Cα Mediates Erlotinib Resistance in Lung Cancer Cells
Overexpression and mutational activation of the epidermal growth factor receptor (EGFR) plays an important role in the pathogenesis of non–small cell lung cancer (NSCLC). EGFR tyrosine-kinase inhibitors (TKIs) are given as a primary therapy for advanced patients with EGFR-activating mutations; howev...
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| Publicado no: | Mol Pharmacol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4407729/ https://ncbi.nlm.nih.gov/pubmed/25724832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.115.097725 |
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