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Non-Small Cell Lung Carcinoma Cell Motility, Rac Activation and Metastatic Dissemination Are Mediated by Protein Kinase C Epsilon
BACKGROUND: Protein kinase C (PKC) ε, a key signaling transducer implicated in mitogenesis, survival, and cancer progression, is overexpressed in human primary non-small cell lung cancer (NSCLC). The role of PKCε in lung cancer metastasis has not yet been established. PRINCIPAL FINDINGS: Here we sho...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288050/ https://ncbi.nlm.nih.gov/pubmed/22384062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031714 |
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